Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors

Wang, Daniel; Salem, Joe‐Elie; V. Cohen, Justine; Chandra, Sunandana; Menzer, Christian; Ye, Fei; Zhao, Shilin; Das, Satya; E. Beckermann, Kathryn; Ha, Lisa; Kimryn Rathmell, W.; Kathleen Ancell, Kristin; M. Balko, Justin; Bowman, Caitlin; J. Davis, Elizabeth; D. Chism, David; Horn, Leora; V. Long, Georgina; S. Carlino, Matteo; Lebrun‐Vignes, Bénédicte; Eroglu, Zeynep; C. Hassel, Jessica; M. Menzies, Alexander; A. Sosman, Jeffrey; J. Sullivan, Ryan; J. Moslehi, Javid; B. Johnson, Douglas

doi:10.1001/jamaoncol.2018.3923

Public

Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors

Published in JAMA Oncology • Sep 18, 2018

Authors:

Daniel Wang

Joe‐Elie Salem

Justine V. Cohen

Abstract

Importance: Immune checkpoint inhibitors (ICIs) are now a mainstay of cancer treatment. Although rare, fulminant and fatal toxic effects may complicate these otherwise transformative therapies; characterizing these events requires integration of global data. Objective: To determine the spectrum, tim...

Subject

Medicine

Ipilimumab

Durvalumab

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