Ceftazidime‐Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups

Li, Jianguo; Lovern, Mark; L. Green, Michelle; Chiu, Joannellyn; Zhou, Diansong; Comisar, Craig; Xiong, Yuan; Hing, Jeremy; MacPherson, Merran; G. Wright, James; Riccobene, Todd; J. Carrothers, Timothy; Das, Shampa

doi:10.1111/cts.12585

Public

Ceftazidime‐Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups

Shared by NobleBlocks on Sep 28, 2018 • 12:00 AM UTC

Authors:

Jianguo Li

Mark Lovern

Michelle L. Green

Abstract

Ceftazidime‐avibactam is a novel β‐lactam/β‐lactamase inhibitor combination for the treatment of serious infections caused by resistant gram‐negative pathogens. Population pharmacokinetic (Pop PK ) models were built to incorporate pharmacokinetic ( PK ) data from five phase III trials in patients wi...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!