RETRACTED ARTICLE: Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress

Zhang, Xiaodong; Li, Yan; Ma, Yingbo; Yang, Liang; Wang, Tao; Meng, Xin; Zong, Zhi‐Hong; Sun, Xun; Hua, Xiangdong; Li, Hangyu

doi:10.1186/s13046-018-0892-2

Public

RETRACTED ARTICLE: Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress

Published in Journal of Experimental & Clinical Cancer Research • Sep 4, 2018

Authors:

Xiaodong Zhang

Yan Li

Yingbo Ma

Abstract

Abstract Background Hypoxia-inducible factor 1α (HIF-1α) is essential in hepatocellular carcinoma (HCC) glycolysis and progression. Yes-associated protein (YAP) is a powerful regulator and is overexpressed in many cancers, including HCC. The regulatory mechanism of YAP and HIF-1α in HCC glycolysis i...

Subject

Gene knockdown

Glycolysis

Cancer research

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!