Discriminative Accuracy of [<sup>18</sup>F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders

Ossenkoppele, Rik; D. Rabinovici, Gil; Smith, Ruben; Cho, Hanna; Schöll, Michael; Strandberg, Olof; Palmqvist, Sebastian; Mattsson, Niklas; Janelidze, Shorena; Santillo, Alexander; Ohlsson, Tomas; Jögi, Jonas; Tsai, Richard; La Joie, Renaud; H. Kramer, Joel; L. Boxer, Adam; Luisa Gorno‐Tempini, Maria; L. Miller, Bruce; Yong Choi, Jae; Hoon Ryu, Young; Hyoung Lyoo, Chul; Hansson, Oskar

doi:10.1001/jama.2018.12917

Public

Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders

Published in JAMA • Sep 18, 2018

Authors:

Rik Ossenkoppele

Gil D. Rabinovici

Ruben Smith

Abstract

Importance: The positron emission tomography (PET) tracer [18F]flortaucipir allows in vivo quantification of paired helical filament tau, a core neuropathological feature of Alzheimer disease (AD), but its diagnostic utility is unclear. Objective: To examine the discriminative accuracy of [18F]flort...

Subject

Medicine

Positron emission tomography

Dementia

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