Naturally Occurring Acetylcholinesterase Inhibitors and Their Potential Use for Alzheimer's Disease Therapy

Coelho dos Santos, Thaiane; Mota Gomes, Thaís; Pinto, Bruno; Leandro Camara, Adriana; Marcus de Andrade Paes, Antonio

doi:10.3389/fphar.2018.01192

Public

Naturally Occurring Acetylcholinesterase Inhibitors and Their Potential Use for Alzheimer's Disease Therapy

Published in Frontiers in Pharmacology • Oct 18, 2018

Authors:

Thaiane Coelho dos Santos

Thaís Mota Gomes

Bruno Pinto

Abstract

Alzheimer's disease (AD) is a main cause of dementia, accounting for up to 75% of all dementia cases. Pathophysiological processes described for AD progression involve neurons and synapses degeneration, mainly characterized by cholinergic impairment. This feature makes acetylcholinesterase inhibitor...

Subject

Acetylcholinesterase

Medicine

Disease

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