Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial

Salminen, Paulina; Tuominen, Risto; Paajanen, Hannu; Rautio, Tero; Nordström, Pia; Aarnio, Markku; Rantanen, Tuomo; Hurme, Saija; Mecklin, Jukka‐Pekka; Sand, Juhani; Virtanen, Johanna; Jartti, Airi; Grönroos, Juha

doi:10.1001/jama.2018.13201

Public

Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial

Published in JAMA • Sep 25, 2018

Authors:

Paulina Salminen

Risto Tuominen

Hannu Paajanen

Abstract

Importance: Short-term results support antibiotics as an alternative to surgery for treating uncomplicated acute appendicitis, but long-term outcomes are not known. Objective: To determine the late recurrence rate of appendicitis after antibiotic therapy for the treatment of uncomplicated acute appe...

Subject

Medicine

Randomized controlled trial

Appendicitis

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