Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after initiating treat-to-target tocilizumab, methotrexate, or the combination: insights from systems biology

M Teitsma, Xavier; Yang, Wei; W. G. Jacobs, Johannes; Pethö‐Schramm, Attila; E A Borm, Michelle; C. Harms, Amy; Hankemeier, Thomas; M. van Laar, Jacob; W. J. Bijlsma, J.; P. J. G. Lafeber, Floris

doi:10.1186/s13075-018-1729-2

Public

Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after initiating treat-to-target tocilizumab, methotrexate, or the combination: insights from systems biology

Published in Arthritis Research & Therapy • Oct 15, 2018

Authors:

Xavier M Teitsma

Wei Yang

Johannes W. G. Jacobs

Abstract

BACKGROUND: We previously identified, in newly diagnosed rheumatoid arthritis (RA) patients, networks of co-expressed genes and proteomic biomarkers associated with achieving sustained drug-free remission (sDFR) after treatment with tocilizumab- or methotrexate-based strategies. The aim of this stud...

Subject

Tocilizumab

Methotrexate

Rheumatoid arthritis

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