Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury

James Cooper, D.; Nichol, Alistair; Bailey, Michael; Bernard, Stephen; Cameron, Peter; Pili‐Floury, Sébastien; Forbes, Andrew; Gantner, Dashiell; M. Higgins, Alisa; Huet, Olivier; Kasza, Jessica; Murray, Lynne; Newby, Lynette; Presneill, Jeffrey; Rashford, Stephen; V. Rosenfeld, Jeffrey; Stephenson, Michael; Vallance, Shirley; Varma, Dinesh; Webb, Steven; Trapani, Tony; McArthur, Colin

doi:10.1001/jama.2018.17075

Public

Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury

Published in JAMA • Oct 25, 2018

Authors:

D. James Cooper

Alistair Nichol

Michael Bailey

Abstract

Importance: After severe traumatic brain injury, induction of prophylactic hypothermia has been suggested to be neuroprotective and improve long-term neurologic outcomes. Objective: To determine the effectiveness of early prophylactic hypothermia compared with normothermic management of patients aft...

Subject

Medicine

Randomized controlled trial

Hypothermia

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