M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole

Huang, Ning; Zhang, Donghui; Li, Fangyuan; Chai, Peiyuan; Wang, Song; Teng, Junlin; Chen, Jianguo

doi:10.1038/s41467-018-06990-9

Public

M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole

Published in Nature Communications • Oct 24, 2018

Authors:

Ning Huang

Donghui Zhang

Fangyuan Li

Abstract

The primary cilium is elongated from the mother centriole and has diverse signaling roles during development and disease. The CP110-CEP97 complex functions as a negative regulator of ciliogenesis, although the mechanisms regulating its mother centriole localization are poorly understood. Here we sho...

Subject

Ciliogenesis

Cell biology

Phosphoprotein

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