Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU

Krag, Mette; Marker, Søren; Perner, Anders; Wetterslev, Jørn; P. Wise, Matt; C. Schefold, Joerg; Keus, Frederik; Berit Guttormsen, Anne; Bendel, Stepani; Borthwick, Mark; Lange, Theis; Steen Rasmussen, Bodil; Siegemund, Martin; Bundgaard, Helle; Elkmann, Thomas; V. Jensen, Jacob; D. Nielsen, Rune; Liboriussen, Lisbeth; H. Bestle, Morten; M. Elkjær, Jeanie; Fris Palmqvist, Dorte; Bäcklund, Minna; Henrik Laake, Jon; Martin Bådstøløkken, Per; Grönlund, Juha; Breum, Olena; Walli, Akil; Winding, Robert; Iversen, Susanne; Jarnvig, Inge-Lise; O. White, Jonathan; Brand, Björn; B. Madsen, Martin; Quist, Lars; Thornberg, Klaus; Møller, Anders; Wiis, Jørgen; Granholm, Anders; Thomas Anthon, Carl; Sylvest Meyhoff, Tine; Buhl Hjortrup, Peter; Rosborg Aagaard, Søren; Bønding Andreasen, Jo; Ankjær Sørensen, Christina; Haure, Pernille; Hauge, Jacob; Hollinger, Alexa; Scheuzger, Jonas; Tuchscherer, Daniel; Vuilliomenet, Thierry; Takala, Jukka; M. Jakob, Stephan; Vang, Marianne; Pælestik, Kim; L.D. Andersen, Karen; C.C. van der Horst, Iwan; Dieperink, Willem; Fjølner, Jesper; K. W. Kjer, Cilia; Sølling, Christine; Sølling, Christoffer; Karttunen, Johanna; Morgan, Matt; Sjøbø, Brit; Engstrøm, Janus; Agerholm-Larsen, Birgit; Hylander Møller, Morten

doi:10.1056/nejmoa1714919

Public

Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU

Published in New England Journal of Medicine • Oct 24, 2018

Authors:

Mette Krag

Søren Marker

Anders Perner

Abstract

BACKGROUND: Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear. METHODS: In this European, multicenter, parallel-group, blinded trial, we randomly assigned adults who had been admitted to the ICU...

Subject

Pantoprazole

Medicine

Gastrointestinal bleeding

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