A computational framework to study sub-cellular RNA localization

Samacoïts, Aubin; Chouaib, Racha; Safieddine, Adham; Traboulsi, Abdel-Meneem; Ouyang, Wei; Zimmer, Christophe; Peter, Marion; Bertrand, Édouard; Walter, Thomas; Mueller, Florian

doi:10.1038/s41467-018-06868-w

Public

A computational framework to study sub-cellular RNA localization

Published in Nature Communications • Oct 29, 2018

Authors:

Aubin Samacoïts

Racha Chouaib

Adham Safieddine

Abstract

RNA localization is a crucial process for cellular function and can be quantitatively studied by single molecule FISH (smFISH). Here, we present an integrated analysis framework to analyze sub-cellular RNA localization. Using simulated images, we design and validate a set of features describing diff...

Subject

RNA

Subcellular localization

Computational biology

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