Randomized Trial of Platelet-Transfusion Thresholds in Neonates

Curley, Anna; Stanworth, Simon; A. Willoughby, Karen; F. Fustolo‐Gunnink, Susanna; Venkatesh, Vidheya; Hudson, Cara; Deary, Alison; Hodge, Renate; Hopkins, Valerie; Lopez Santamaria, Beatriz; Sabrina Mora, Ana; Llewelyn, Charlotte; D’Amore, Angela; Khan, Rizwan; Onland, Wes; Lopriore, Enrico; Fijnvandraat, Karin; New, Helen; Clarke, Paul; J. Watts, Timothy

doi:10.1056/nejmoa1807320

Public

Randomized Trial of Platelet-Transfusion Thresholds in Neonates

Published in New England Journal of Medicine • Nov 2, 2018

Authors:

Anna Curley

Simon Stanworth

Karen A. Willoughby

Abstract

BACKGROUND: Platelet transfusions are commonly used to prevent bleeding in preterm infants with thrombocytopenia. Data are lacking to provide guidance regarding thresholds for prophylactic platelet transfusions in preterm neonates with severe thrombocytopenia. METHODS: In this multicenter trial, we ...

Subject

Medicine

Odds ratio

Randomization

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