Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial

P. Halliday, Brian; Wassall, Rebecca; Lota, Amrit; Khalique, Zohya; Gregson, John; Newsome, Simon; W. Jackson, Robert; Rahneva, Tsveta; Wage, Rick; Smith, Gillian; Venneri, Lucia; Tayal, Upasana; Auger, Dominique; Midwinter, William; Whiffin, Nicola; Rajani, Ronak; Dungu, Jason; Pantazis, Antonis; A. Cook, Stuart; S. Ware, James; John Baksi, A.; J. Pennell, Dudley; D. Rosen, Stuart; Cowie, Martín; G.F. Cleland, John; Prasad, Sanjay

doi:10.1016/s0140-6736(18)32484-x

Public

Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial

Published in The Lancet • Nov 11, 2018

Authors:

Brian P. Halliday

Rebecca Wassall

Amrit Lota

Abstract

BACKGROUND: Patients with dilated cardiomyopathy whose symptoms and cardiac function have recovered often ask whether their medications can be stopped. The safety of withdrawing treatment in this situation is unknown. METHODS: We did an open-label, pilot, randomised trial to examine the effect of ph...

Subject

Medicine

Dilated cardiomyopathy

Ejection fraction

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