Neoadjuvant (Chemo)radiotherapy With Total Mesorectal Excision Only Is Not Sufficient to Prevent Lateral Local Recurrence in Enlarged Nodes: Results of the Multicenter Lateral Node Study of Patients With Low cT3/4 Rectal Cancer

Ogura, Atsushi; Konishi, Tsuyoshi; Cunningham, Chris; García‐Aguilar, Julio; Iversen, Henrik; Toda, Shigeo; Kyu Lee, In; Lee, Hong; Uehara, Keisuke; Lee, Peter; Putter, Hein; J.�H. van de Velde, Cornelis; L. Beets, Geerard; Rutten, H.J.T.; Kusters, Miranda

doi:10.1200/jco.18.00032

Public

Neoadjuvant (Chemo)radiotherapy With Total Mesorectal Excision Only Is Not Sufficient to Prevent Lateral Local Recurrence in Enlarged Nodes: Results of the Multicenter Lateral Node Study of Patients With Low cT3/4 Rectal Cancer

Published in Journal of Clinical Oncology • Nov 7, 2018

Authors:

Atsushi Ogura

Tsuyoshi Konishi

Chris Cunningham

Abstract

PURPOSE: Improvements in magnetic resonance imaging (MRI), total mesorectal excision (TME) surgery, and the use of (chemo)radiotherapy ([C]RT) have improved local control of rectal cancer; however, we have been unable to eradicate local recurrence (LR). Even in the face of TME and negative resection...

Subject

Medicine

Total mesorectal excision

Radiation therapy

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