Unloading the Left Ventricle Before Reperfusion in Patients With Anterior ST-Segment–Elevation Myocardial Infarction

K. Kapur, Navin; A. Alkhouli, Mohamad; J. DeMartini, Tony; Faraz, Haroon; H. George, Zachary; J. Goodwin, Mark; A. Hernandez-Montfort, Jaime; S. Iyer, Vijay; Josephy, Noam; Kalra, Sanjog; Kaki, Amir; H. Karas, Richard; D. Kimmelstiel, Carey; C. Koenig, Gerald; Lau, Evan; Lotun, Kapildeo; D. Madder, Ryan; F. Mannino, Salvatore; M. Meraj, Perwaiz; A. Moreland, Jason; W. Moses, Jeffrey; L. Kim, Raymond; L. Schreiber, Theodore; E. Udelson, James; Witzke, Christian; H.W. Wohns, David; W. O’Neill, William

doi:10.1161/circulationaha.118.038269

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Unloading the Left Ventricle Before Reperfusion in Patients With Anterior ST-Segment–Elevation Myocardial Infarction

Shared by NobleBlocks on Jan 15, 2019 • 12:00 AM UTC

Authors:

Navin K. Kapur

Mohamad A. Alkhouli

Tony J. DeMartini

Abstract

Background: In ST-segment–elevation myocardial infarction (STEMI), infarct size correlates directly with heart failure and mortality. Preclinical testing has shown that, in comparison with reperfusion alone, mechanically unloading the left ventricle (LV) before reperfusion reduces infarct size and t...

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