Decreased microRNA-182-5p helps alendronate promote osteoblast proliferation and differentiation in osteoporosis via the Rap1/MAPK pathway

Pan, Baolong; Tong, Zongwu; Li, Shu-De; Wu, Ling; Liao, Jun-Long; Yang, Yuxi; Li, Hu-Huan; Dai, Yan-Juan; Li, June; Li, Pan

doi:10.1042/bsr20180696

Public

Decreased microRNA-182-5p helps alendronate promote osteoblast proliferation and differentiation in osteoporosis via the Rap1/MAPK pathway

Published in Bioscience Reports • Nov 9, 2018

Authors:

Baolong Pan

Zongwu Tong

Shu-De Li

Abstract

Osteoporosis (OP) is a serious health problem that contributes to osteoporotic structural damage and bone fragility. MicroRNAs (miRNAs) can exert important functions over bone endocrinology. Therefore, it is of substantial significance to clarify the expression and function of miRNAs in bone endocri...

Subject

Rap1

Osteoblast

MAPK/ERK pathway

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