Genomic analyses in African populations identify novel risk loci for cleft palate

Butali, Azeez; Mossey, Peter; Lanre Adeyemo, Wasiu; Eshete, Mekonen; Jephthah Joojo Gowans, Lord; Busch, Tamara; Jain, Deepti; Yu, Wenjie; Liu, Huan; Laurie, Cecelia; C. Laurie, Cathy; C. Nelson, Sarah; Li, Mary; A. Sanchez‐Lara, Pedro; P. Magee, William; Magee, Kathleen; Auslander, Allyn; Brindopke, Frederick; M. Kay, Denise; Caggana, Michele; A. Romitti, Paul; L. Mills, James; Audu, Rosemary; Onwuamah, Chika; Oseni, G.O.; Owais, Arwa; James, Olutayo; B Olaitan, Peter; S. Aregbesola, Babatunde; Oyebunmi Braimah, Ramat; Olufunmilayo Oginni, Fadekemi; O. Oladele, Ayodeji; Bello, S.A.; Rhodes, Jennifer; Shiang, Rita; Donkor, Peter; Obiri‐Yeboah, Solomon; K. N. Arthur, Fareed; Twumasi, Peter; Agbenorku, Pius; Plange‐Rhule, Gyikua; Acheampong Oti, Alexander; M. Ogunlewe, Olugbenga; A. Oladega, Afisu; Adeola Adekunle, Adegbayi; Erinoso, Olufemi; Adamson, Olawale; A Elufowoju, Abosede; Ayelomi, Oluwanifemi; Hailu, Taiye; Hailu, Abiye; Demissie, Yohannes; Derebew, Miliard; Eliason, Steve; Romero-Bustillous, Miguel; Lo, Cynthia; O. Park, James; Desai, S.; Mohammed, Muiawa; Abate, Firke; Abdur-Rahman, LO; Anand, Deepti; Saadi, Irfan; Victoria Oladugba, Abimibola; A. Lachke, Salil; A. Amendt, Brad; N. Rotimi, Charles; L. Marazita, Mary; A. Cornell, Robert; C. Murray, Jeffrey; Adeyemo, Adebowale

doi:10.1093/hmg/ddy402

Public

Genomic analyses in African populations identify novel risk loci for cleft palate

Published in Human Molecular Genetics • Nov 16, 2018

Authors:

Azeez Butali

Peter Mossey

Wasiu Lanre Adeyemo

Abstract

Orofacial clefts are common developmental disorders that pose significant clinical, economical and psychological problems. We conducted genome-wide association analyses for cleft palate only (CPO) and cleft lip with or without palate (CL/P) with ~17 million markers in sub-Saharan Africans. After rep...

Subject

Biology

Locus (genetics)

Genetics

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