CircSLC3A2 functions as an oncogenic factor in hepatocellular carcinoma by sponging miR-490-3p and regulating PPM1F expression.

H, Wang; W, Chen; M, Jin; L, Hou; X, Chen; R, Zhang; J, Zhang; J, Zhu

doi:10.1186/s12943-018-0909-7

Public

CircSLC3A2 functions as an oncogenic factor in hepatocellular carcinoma by sponging miR-490-3p and regulating PPM1F expression.

Shared by NobleBlocks on Nov 23, 2018 • 12:00 AM UTC

Authors:

Wang H

Chen W

Jin M

Abstract

Background Non-coding RNAs (ncRNAs) have been reported to participate in tumor progression by regulating gene expression. Previous studies showed that protein phosphatase Mg2+/Mn2+ dependent 1F (PPM1F) acts a dual role in cancer growth and metastasis. But, the underlying mechanisms by which ncRNAs r...

Subject

Hepatocellular carcinoma

Proliferation

Invasion

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