Polymethine Thiopyrylium Fluorophores with Absorption beyond 1000 nm for Biological Imaging in the Second Near-Infrared Subwindow

Ding, Bingbing; Xiao, Yuling; Zhou, Hui; Zhang, Xiao; Qu, Chunrong; Xu, Fuchun; Deng, Zixin; Cheng, Zhen; Hong, Xuechuan

doi:10.1021/acs.jmedchem.8b01682

Public

Polymethine Thiopyrylium Fluorophores with Absorption beyond 1000 nm for Biological Imaging in the Second Near-Infrared Subwindow

Published in Journal of Medicinal Chemistry • Dec 2, 2018

Authors:

Bingbing Ding

Yuling Xiao

Hui Zhou

Abstract

Small-molecule fluorescence imaging in the second near-infrared (NIR-II, 1000-1700 nm) window has gained increasing interest in clinical application. Till now, very few studies have been exploited in the small-molecule fluorophores with both excitation and emission in the NIR-II window. Inspired by ...

Subject

Fluorophore

Chemistry

Near-infrared spectroscopy

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