Brain-Specific Ultrastructure of Capillary Endothelial Glycocalyx and Its Possible Contribution for Blood Brain Barrier

Ando, Yoshiaki; Okada, Hideshi; Takemura, Genzou; Suzuki, Kodai; Takada, Chihiro; Tomita, Hiroyuki; Zaikokuji, Ryogen; Hotta, Yasuaki; Miyazaki, Nagisa; Yano, Hirohisa; Muraki, Isamu; Kuroda, Ayumi; Fukuda, Hirotsugu; Kawasaki, Yuki; Okamoto, Haruka; Kawaguchi, Tomonori; Watanabe, Takatomo; Doi, Tomoaki; Yoshida, Takahiro; Ushikoshi, Hiroaki; Yoshida, Shozo; Ogura, Shinji

doi:10.1038/s41598-018-35976-2

Public

Brain-Specific Ultrastructure of Capillary Endothelial Glycocalyx and Its Possible Contribution for Blood Brain Barrier

Published in Scientific Reports • Nov 26, 2018

Authors:

Yoshiaki Ando

Hideshi Okada

Genzou Takemura

Abstract

Endothelial glycocalyx coats healthy vascular endothelium and plays an important role in vascular homeostasis. Although cerebral capillaries are categorized as continuous, as are those in the heart and lung, they likely have specific features related to their function in the blood brain barrier. To ...

Subject

Glycocalyx

Blood–brain barrier

Endothelium

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