Amelioration of clinical symptoms of patients with refractory rheumatoid arthritis following treatment with autologous bone marrow-derived mesenchymal stem cells: A successful clinical trial in Iran

Ghoryani, Mohsen; Shariati‐Sarabi, Zhaleh; Tavakkol‐Afshari, Jalil; Ghasemi, Ali; Poursamimi, Javad; Mohammadi, Mojgan

doi:10.1016/j.biopha.2018.11.056

Public

Amelioration of clinical symptoms of patients with refractory rheumatoid arthritis following treatment with autologous bone marrow-derived mesenchymal stem cells: A successful clinical trial in Iran

Published in Biomedicine & Pharmacotherapy • Nov 26, 2018

Authors:

Mohsen Ghoryani

Zhaleh Shariati‐Sarabi

Jalil Tavakkol‐Afshari

Abstract

autologous bone marrow-derived MSCs/kg, and were followed up at 1, 6 and 12 months after injection of MSCs. We found a significant decreasing trend in Th17 percentage and geometric mean fluorescence intensity for IL-17A following injection of MSCs at 12 months compared to the time point zero. Furthe...

Subject

Medicine

Mesenchymal stem cell

Rheumatoid arthritis

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