A DNA methylation reader complex that enhances gene transcription

Jake Harris, C.; Scheibe, Marion; Pop Wongpalee, Somsakul; Liu, Wanlu; M. Cornett, Evan; M. Vaughan, Robert; Li, Xueqin; Chen, Wei; Xue, Yan; Zhong, Zhenhui; Yen, Linda; D. Barshop, William; Rayatpisheh, Shima; Gallego-Bartolome, Javier; Groth, Martin; Wang, Zonghua; A. Wohlschlegel, James; Du, Jiamu; B. Rothbart, Scott; Butter, Falk; E. Jacobsen, Steven

doi:10.1126/science.aar7854

Public

A DNA methylation reader complex that enhances gene transcription

Shared by NobleBlocks on Dec 7, 2018 • 12:00 AM UTC

Authors:

C. Jake Harris

Marion Scheibe

Somsakul Pop Wongpalee

Abstract

DNA methylation promotes transcription DNA methylation generally represses transcription, but in some instances, it has also been implicated in transcription activation. Harris et al. identified a protein complex in Arabidopsis that is recruited to chromatin by DNA methylation. This complex specific...

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