The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa

Eun Park, Se; Thanh Pham, Duy; Boinett, Christine; K. Wong, Vanessa; Deok Pak, Gi; Panzner, Ursula; Maria Cruz Espinoza, Ligia; von Kalckreuth, Vera; Im, Justin; Schütt-Gerowitt, Heidi; A. Crump, John; F. Breiman, Robert; Adu-Sarkodie, Yaw; Owusu-Dabo, Ellis; Rakotozandrindrainy, Raphaël; Bassiahi Soura, Abdramane; Aseffa, Abraham; Gasmelseed, Nagla; H. Keddy, Karen; May, Jürgen; Gassama Sow, Amy; Aaby, Peter; M. Biggs, Holly; T. Hertz, Julian; M. Montgomery, Joel; Cosmas, Leonard; Olack, Beatrice; Fields, Barry; Sarpong, Nimako; Jean Luco Razafindrabe, Tsiriniaina; Mirana Raminosoa, Tiana; Parfait Kabore, Leon; Sampo, Emmanuel; Teferi, Mekonnen; Yeshitela, Biruk; Ahmed El Tayeb, Muna; Sooka, Arvinda; G. Meyer, Christian; Krumkamp, Ralf; Myriam Dekker, Denise; Jaeger, Anna; Poppert, Sven; Tall, Adama; Niang, Aissatou; Bjerregaard-Andersen, Morten; Valborg Løfberg, Sandra; Jin Seo, Hye; Jin Jeon, Hyon; Fung Deerin, Jessica; Park, Jinkyung; Konings, Frank; Ali, Mohammad; D. Clemens, John; Hughes, Peter; Nsimire Sendagala, Juliet; Vudriko, Tobias; Downing, Robert; N. Ikumapayi, Usman; A. Mackenzie, Grant; Obaro, Stephen; Argimon, Silvia; M. Aanensen, David; Page, Andrew; A. Keane, Jacqueline; Duchene, Sebastian; Dyson, Zoe; E. Holt, Kathryn; Dougan, Gordon; Marks, Florian; Baker, Stephen

doi:10.1038/s41467-018-07370-z

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The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa

Shared by NobleBlocks on Nov 28, 2018 • 12:00 AM UTC

Authors:

Se Eun Park

Duy Thanh Pham

Christine Boinett

Abstract

Abstract There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa. Here we present a phylogenetic reconstruction of whole genome sequenced 249 contemporaneous S . Typhi isolated between 2008-20...

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