Safety evaluation of frequent application of microbubble-enhanced focused ultrasound blood-brain-barrier opening

Tsai, Hong‐Chieh; Tsai, Chih-Hung; Chen, Wen‐Shiang; Inserra, Claude; Wei, Kuo‐Chen; Liu, Hao-Li

doi:10.1038/s41598-018-35677-w

Public

Safety evaluation of frequent application of microbubble-enhanced focused ultrasound blood-brain-barrier opening

Published in Scientific Reports • Dec 3, 2018

Authors:

Hong‐Chieh Tsai

Chih-Hung Tsai

Wen‐Shiang Chen

Abstract

Focused ultrasound (FUS) with the presence of microbubbles induces blood brain barrier (BBB) opening in targeted areas and facilitates drug delivery. However, recent studies have indicated that FUS-BBB opening with excessive exposure levels may be associated with inflammatory response and cellular/t...

Subject

Microbubbles

Medicine

Ultrasound

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!