Opioids for Chronic Noncancer Pain

W. Busse, Jason; Wang, Li; Kamaleldin, Mostafa; Craigie, Samantha; J. Riva, John; Montoya, Luis; Mulla, Sohail; Cruz Lopes, Luciane; Vogel, Nicole; Chen, Eric; Kirmayr, Karin; De Oliveira, Kyle; Olivieri, Lori; Kaushal, Alka; Enrique Chaparro, Luis; Oyberman, Inna; Agarwal, Arnav; Couban, Rachel; Tsoi, Ludwig; Lam, Tommy; Olav Vandvik, Per; Hsu, Sandy; M Bała, Małgorzata; Schandelmaier, Stefan; Scheidecker, Anne; Ebrahim, Shanil; Ashoorion, Vahid; Rehman, Yasir; Jiho Hong, Patrick; Ross, Stephanie; C. Johnston, Bradley; Kunz, Regina; Sun, Xin; Buckley, Norman; I. Sessler, Daniel; Guyatt, Gordon

doi:10.1001/jama.2018.18472

Public

Opioids for Chronic Noncancer Pain

Published in JAMA • Dec 18, 2018

Authors:

Jason W. Busse

Li Wang

Mostafa Kamaleldin

Abstract

Importance: Harms and benefits of opioids for chronic noncancer pain remain unclear. Objective: To systematically review randomized clinical trials (RCTs) of opioids for chronic noncancer pain. Data Sources and Study Selection: The databases of CENTRAL, CINAHL, EMBASE, MEDLINE, AMED, and PsycINFO we...

Subject

Medicine

Placebo

Visual analogue scale

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