Integrative functional genomic analysis of human brain development and neuropsychiatric risks

Li, Mingfeng; Santpere, Gabriel; Imamura Kawasawa, Yuka; V. Evgrafov, Oleg; O. Gulden, Forrest; Pochareddy, Sirisha; M. Sunkin, Susan; Li, Zhen; Shin, Yurae; Zhu, Ying; M. M. Sousa, André; M. Werling, Donna; R. Kitchen, Robert; Jung Kang, Hyo; Pletikos, Mihovil; Choi, Jinmyung; K. Muchnik, Sydney; Xu, Xuming; Wang, Daifeng; Lorente-Galdós, Belén; Liu, Shuang; Giusti‐Rodríguez, Paola; Won, Hyejung; de Leeuw, Christiaan; F. Pardiñas, Antonio; Developmental Subgroup, PsychENCODE; Hu, Ming; Jin, Fulai; Li, Yun; J. Owen, Michael; O‘Donovan, Michael; Walters, James; Posthuma, Daniëlle; A. Reimers, Mark; Levitt, Pat; R. Weinberger, Daniel; M. Hyde, Thomas; E. Kleinman, Joel; H. Geschwind, Daniel; Hawrylycz, Michael; W. State, Matthew; Sanders, Stephan; F. Sullivan, Patrick; Gerstein, Mark; S. Lein, Ed; A. Knowles, James; Šestan, Nenad; Jeremy Willsey, A.; Oldre, Aaron; Szafer, Aaron; Camarena, Adrian; Cherskov, Adriana; W. Charney, Alexander; Abyzov, Alexej; Kozlenkov, Alexey; Safi, Alexias; R. Jones, Allan; E. Ashley‐Koch, Allison; Ebbert, Amanda; J. Price, Amanda; Sekijima, Amanda; Kefi, Amira; Bernard, Amy; Amiri, Anahita; Sboner, Andrea; E. Clark, Andrew; E. Jaffe, Andrew; T.N. Tebbenkamp, Andrew; J. Sodt, Andy; Guillozet‐Bongaarts, Angie; C. Nairn, Angus; Carey, Anita; Hüttner, Anita; Chervenak, Ann; Szekely, Anna; W. Shieh, Annie; Harmanci, Arif; K. Lipska, Barbara; C. Carlyle, Becky; W. Gregor, Ben; Kassim, Bibi; Sheppard, Brooke; Bichsel, Candace; Hahn, Chang-Gyu; Lee, Chang-Kyu; Chen, Chao; L. Kuan, Chihchau; Dang, Chinh; Lau, Chris; Cuhaciyan, Christine; Armoskus, Christoper; E. Mason, Christopher; Liu, Chunyu; Slaughterbeck, Cliff; Bennet, Crissa; Pinto, Dalila; Polioudakis, Damon; Franjic, Daniel; J. Miller, Daniel; Bertagnolli, Darren; A. Lewis, David; Feng, David; Sandman, David; Clarke, Declan; Williams, Derric; M. Del Valle, Diane; Fitzgerald, Dominic; Shen, Elaine; Flatow, Elie; Zharovsky, Elizabeth; E. Burke, Emily; C. Olson, Eric; Fulfs, Erich; Mattei, Eugenio; Hadjimichael, Evi; Deelman, Ewa; C. P. Navarro, Fábio; Wu, Feinan; Lee, Felix; Cheng, Feng; S. Goes, Fernando; M. Vaccarino, Flora; Liu, Fuchen; E. Hoffman, Gabriel; Gürsoy, Gamze; Gee, Garrett; Mehta, Gaurang; Coppola, Gianfilippo; Giase, Gina; Sedmak, Goran; D. Johnson, Graham; A. Wray, Gregory; E. Crawford, Gregory; Gu, Guangyu; van Bakel, Harm; Witt, Heather; Jae Yoon, Hee; Pratt, Henry; Zhao, Hongyu; A. Glass, Ian; Huey, Jack; M. Arnold, James; P. Noonan, James; Bendl, Jaroslav; M. Jochim, Jayson; Goldy, Jeff; Herstein, Jennifer; Wiseman, Jennifer; A. Miller, Jeremy; Mariani, Jessica; Stoll, Jessica; Russell Moore, J.; Szatkiewicz, Jin; Leng, Jing; Zhang, Jing; Parente, Jody; Rozowsky, Joel; F. Fullard, John; G. Hohmann, John; C. Morris, John; W. Phillips, John; Warrell, Jonathan; Heon Shin, Joo; An, Joon‐Yong; Belmont, Judson; Nyhus, Julie; Pendergraft, Julie; Bryois, Julien; Roll, Katie; Grennan, Kay; Aiona, Kaylynn; P. White, Kevin; A. Aldinger, Kimberly; A. Smith, Kimberly; Girdhar, Kiran; Brouner, Kristina; M. Mangravite, Lara; Brown, Leanne; Collado‐Torres, Leonardo; Cheng, Lijun; Gourley, Lindsey; Song, Lingyun; de la Torre-Ubieta, Luis; Habegger, Lukas; Ng, Lydia; E. Hauberg, Mads; Onorati, Marco; J. Webster, Maree; Kundaković, Marija; Škarica, Mario; Reimers, Mark; B. Johnson, Matthew; Chen, Maxine; E. Garrett, Melanie; Sarreal, Melanie; Reding, Melissa; Gu, Mengting; A. Peters, Mette; Fisher, Michael; J. Gandal, Michael; Purcaro, Michael; W. Smith, Michael; Brown, Miguel; Shibata, Mikihito; Brown, Mimi; Xu, Min; Yang, Mo; Ray, Mohana; V. Shapovalova, Nadiya; Francoeur, Nancy; Sjoquist, Nathan; Mastan, Naveed; Kaur, Navjot; Parikshak, Neelroop; F. Mosqueda, Nerick; Ngo, Nhan-Kiet; Dee, Nick; A. Ivanov, Nikolay; Devillers, Olivia; Roussos, Panos; D. Parker, Patrick; Manser, Paul; Wohnoutka, Paul; Farnham, Peggy; P. Zandi, Peter; S. Emani, Prashant; Dalley, Rachel; Mayani, Rajiv; Tao, Ran; Gittin, Reaghan; E. Straub, Richard; P. Lifton, Richard; Jacobov, Rivka; Howard, Robert; Park, Royce; Dai, Rujia; Abramowicz, Sandra; Akbarian, Schahram; Schreiner, Shannon; Ma, Shaojie; Parry, Sheana; Shapouri, Sheila; M. Weissman, Sherman; Caldejon, Shiella; Mane, Shrikant; Ding, Song‐Lin; Scuderi, Soraya; Dracheva, Stella; Butler, Stephanie; Lisgo, Steven; K. Rhie, Suhn; Lindsay, Susan; Datta, Suvro; Souaiaia, Tade; Roychowdhury, Tanmoy; García Gómez, Teresa; Naluai-Cecchini, Theresa; G. Beach, Thomas; Goodman, Thomas; Gao, Tianliuyun; Dolbeare, Tim; Fliss, Tim; E. Reddy, Timothy; Chen, Ting; M. Hyde, Tom; M. Brunetti, Tonya; Lemon, Tracy; Desta, Tsega; Borrman, Tyler; Haroutunian, Vahram; N. Spitsyna, Valeria; Swarup, Vivek; Shi, Xu; Jiang, Yan; Xia, Yan; Chen, Yang-Ho; Jiang, Yi; Wang, Yongjun; Chae, Yooree; Yang, Yucheng; Kim, Yunjung; L. Riley, Zack; Krsnik, Željka; Deng, Zemin; Weng, Zhiping; Lin, Zhixiang; Li, Zhuo

doi:10.1126/science.aat7615

Public

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

Published in Science • Dec 14, 2018

Authors:

Mingfeng Li

Gabriel Santpere

Yuka Imamura Kawasawa

Abstract

INTRODUCTION The brain is responsible for cognition, behavior, and much of what makes us uniquely human. The development of the brain is a highly complex process, and this process is reliant on precise regulation of molecular and cellular events grounded in the spatiotemporal regulation of the trans...

Subject

Transcriptome

Biology

Neuroscience

Research Assistant

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