Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis

J-DAVID Investigators, The; Shoji, Tetsuo; Inaba, Masaaki; Fukagawa, Masafumi; Ando, Ryoichi; Emoto, Masanori; Fujii, Hisako; Fujimori, Akira; Fukui, Mitsuru; Hase, Hiroki; Hashimoto, Tetsuya; Hirakata, Hideki; Honda, Hirokazu; Hosoya, Tatsuo; Ikari, Yuji; Inaguma, Daijo; Inoue, Toru; Isaka, Yoshitaka; Iseki, Kunitoshi; Ishimura, Eiji; Itami, Noritomo; Ito, Chiharu; Kakuta, Toshitaka; Kawai, Tōru; Kawanishi, Hideki; Kobayashi, Shuzo; Kumagai, Junko; Maekawa, Kiyoshi; Masakane, Ikuto; Minakuchi, Jun; Mitsuiki, Koji; Mizuguchi, Takashi; Morimoto, Satoshi; Murohara, Toyoaki; Nakatani, Tatsuya; Negi, Shigeo; Nishi, Shinichi; Nishikawa, Mitsushige; Ogawa, Tetsuya; Ohta, Kazumichi; Ohtake, Takayasu; Okamura, Mikio; Okuno, Senji; Shigematsu, Takashi; Sugimoto, Toshitsugu; Suzuki, Masashi; Tahara, Hideki; Takemoto, Yoshiaki; Tanaka, K.; Tominaga, Yoshihiro; Tsubakihara, Yoshiharu; Tsujimoto, Yoshihiro; Tsuruya, Kazuhiko; Ueda, Shinichiro; Watanabe, Yuzo; Yamagata, Kunihiro; Yamakawa, Tomoyuki; Yano, Shozo; Yokoyama, Keitaro; Yorioka, Noriaki; Yoshiyama, Minoru; Nishizawà, Yoshiki

doi:10.1001/jama.2018.17749

Public

Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis

Published in JAMA • Dec 11, 2018

Authors:

The J-DAVID Investigators

Tetsuo Shoji

Masaaki Inaba

Abstract

Importance: Patients with chronic kidney disease have impaired vitamin D activation and elevated cardiovascular risk. Observational studies in patients treated with hemodialysis showed that the use of active vitamin D sterols was associated with lower risk of all-cause mortality, regardless of parat...

Subject

Medicine

Internal medicine

Alfacalcidol

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