<i>EGFR</i>
                    -Mutant Adenocarcinomas That Transform to Small-Cell Lung Cancer and Other Neuroendocrine Carcinomas: Clinical Outcomes

Marcoux, Nicolas; N. Gettinger, Scott; O’Kane, Grainne; C. Arbour, Kathryn; W. Neal, Joel; Husain, Hatim; L. Evans, Tracey; R. Brahmer, Julie; Muzikansky, Alona; D. Bonomi, Philip; del Prete, Salvatore; Wurtz, Anna; F. Farago, Anna; Dias-Santagata, Dora; Mino-Kenudson, Mari; L. Reckamp, Karen; A. Yu, Helena; A. Wakelee, Heather; A. Shepherd, Frances; Piotrowska, Zofia; V. Sequist, Lecia

doi:10.1200/jco.18.01585

Public

EGFR -Mutant Adenocarcinomas That Transform to Small-Cell Lung Cancer and Other Neuroendocrine Carcinomas: Clinical Outcomes

Shared by NobleBlocks on Feb 1, 2019 • 12:00 AM UTC

Authors:

Nicolas Marcoux

Scott N. Gettinger

Grainne O’Kane

Abstract

Purpose Approximately 3% to 10% of EGFR (epidermal growth factor receptor) -mutant non–small cell lung cancers (NSCLCs) undergo transformation to small-cell lung cancer (SCLC), but their clinical course is poorly characterized. Methods We retrospectively identified patients with EGFR-mutant SCLC and...

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