ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells

W. Lee, Daniel; Santomasso, Bianca; L. Locke, Frederick; Ghobadi, Armin; J. Turtle, Cameron; N. Brudno, Jennifer; V. Maus, Marcela; H. Park, Jae; Mead, Elena; Z. Pavletic, Steven; Y. Go, William; Eldjerou, Lamis; Gardner, Rebecca; V. Frey, Noelle; J. Curran, Kevin; S. Peggs, Karl; C. Pasquini, Marcelo; F. DiPersio, John; R.M. van den Brink, Marcel; V. Komanduri, Krishna; A. Grupp, Stephan; S. Neelapu, Sattva

doi:10.1016/j.bbmt.2018.12.758

Public

ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells

Published in Biology of Blood and Marrow Transplantation • Dec 25, 2018

Authors:

Daniel W. Lee

Bianca Santomasso

Frederick L. Locke

Abstract

Chimeric antigen receptor (CAR) T cell therapy is rapidly emerging as one of the most promising therapies for hematologic malignancies. Two CAR T products were recently approved in the United States and Europe for the treatment ofpatients up to age 25years with relapsed or refractory B cell acute ly...

Subject

Medicine

Effector

Grading (engineering)

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