Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common <i>TYK2</i> missense variant

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Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

Published in Science Immunology • Dec 14, 2018

Authors:

Stéphanie Boisson‐Dupuis

Noé Ramirez‐Alejo

Zhi Li

selectively disrupts the induction of IFN-γ by IL-23 and is a common monogenic etiology of tuberculosis.

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