Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common
                    <i>TYK2</i>
                    missense variant

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Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

Shared by NobleBlocks on Dec 14, 2018 • 12:00 AM UTC

Authors:

Stéphanie Boisson-Dupuis

Noe Ramirez-Alejo

Zhi Li

Homozygosity for the P1104A missense variant of the TYK2 Janus kinase is common monogenic etiology of primary tuberculosis.

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