An Accessible and Unique Insight into Metastasis Mutational Content Through Whole-exome Sequencing of Circulating Tumor Cells in Metastatic Prostate Cancer

Faugeroux, Vincent; Lefèbvre, Céline; Pailler, Emma; Pierron, Valérie; Marcaillou, Charles; Tourlet, Sébastien; Billiot, Fanny; Doğan, Semih; Oulhen, Marianne; Vielh, Philippe; Rameau, Philippe; Ngo‐Camus, Maud; Massard, Christophe; Laplace‐Builhé, Corinne; Tibbe, Arian; Taylor, Mélissa; Soria, Jean‐Charles; Fizazi, Karim; Loriot, Yohann; Julien, Sylvia; Farace, Françoise

doi:10.1016/j.euo.2018.12.005

Public

An Accessible and Unique Insight into Metastasis Mutational Content Through Whole-exome Sequencing of Circulating Tumor Cells in Metastatic Prostate Cancer

Published in European Urology Oncology • Jan 4, 2019

Authors:

Vincent Faugeroux

Céline Lefèbvre

Emma Pailler

Abstract

BACKGROUND: Genomic analysis of circulating tumor cells (CTCs) could provide a unique and accessible representation of tumor diversity but remains hindered by technical challenges associated with CTC rarity and heterogeneity. OBJECTIVE: To evaluate CTCs as surrogate samples for genomic analyses in m...

Subject

Circulating tumor cell

Prostate cancer

Metastasis

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!