Differences in the rate of nicotine metabolism among smokers with and without HIV.

L Ashare, Rebecca; Thompson, Morgan; Leone, Frank; Metzger, David; Gross, Robert; Mounzer, Karam; F Tyndale, Rachel; Lerman, Caryn; C Mahoney, Martin; Cinciripini, Paul; P George, Tony; G Collman, Ronald; Schnoll, Robert

doi:10.1097/qad.0000000000002127

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Differences in the rate of nicotine metabolism among smokers with and without HIV.

Shared by NobleBlocks on May 1, 2019 • 12:00 AM UTC

Authors:

Rebecca L Ashare

Morgan Thompson

Frank Leone

Abstract

OBJECTIVE: HIV-infected smokers lose more life years to tobacco use than to HIV infection. The nicotine metabolite ratio (NMR), a biomarker of CYP2A6, represents individual variation in the rate at which nicotine is metabolized and is associated with response to smoking cessation treatments. We eval...

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