Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial

Miller, David; Pavitt, Susan; Sharma, Vinay; Forbes, Gordon; Hooper, Richard; Bhattacharya, Siladitya; Kirkman‐Brown, Jackson; Coomarasamy, Arri; Lewis, Sheena; Cutting, Rachel; R. Brison, Daniel; Pacey, Allan; West, Robert; Brian, Kate; K. Griffin, Darren; Khalaf, Yakoub

doi:10.1016/s0140-6736(18)32989-1

Public

Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial

Published in The Lancet • Jan 31, 2019

Authors:

David Miller

Susan Pavitt

Vinay Sharma

Abstract

BACKGROUND: Sperm selection strategies aimed at improving success rates of intracytoplasmic sperm injection (ICSI) include binding to hyaluronic acid (herein termed hyaluronan). Hyaluronan-selected sperm have reduced levels of DNA damage and aneuploidy. Use of hyaluronan-based sperm selection for IC...

Subject

Intracytoplasmic sperm injection

Medicine

Gynecology

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