Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy.

TMD, Sheard; ME, Hurley; J, Colyer; E, White; R, Norman; E, Pervolaraki; KK, Narayanasamy; Y, Hou; HM, Kirton; Z, Yang; L, Hunter; JU, Shim; AH, Clowsley; AJ, Smith; D, Baddeley; C, Soeller; MA, Colman; I, Jayasinghe

doi:10.1021/acsnano.8b08742

Public

Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy.

Shared by NobleBlocks on Feb 8, 2019 • 12:00 AM UTC

Authors:

Sheard TMD

Hurley ME

Colyer J

Abstract

Nanodomains are intracellular foci which transduce signals between major cellular compartments. One of the most ubiquitous signal transducers, the ryanodine receptor (RyR) calcium channel, is tightly clustered within these nanodomains. Super-resolution microscopy has previously been used to visualiz...

Subject

Ryanodine receptor

Expansion Microscopy

Signaling Nanodomains

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!