Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape

Jiang, Xianjie; Wang, Jie; Deng, Xiangying; Xiong, Fang; Ge, Junshang; Xiang, Bo; Wu, Xu; Ma, Jian; Zhou, Ming; Li, Xiaoling; Li, Yong; Li, Guiyuan; Xiong, Wei; Guo, Can; Zeng, Zhaoyang

doi:10.1186/s12943-018-0928-4

Public

Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape

Published in Molecular Cancer • Jan 15, 2019

Authors:

Xianjie Jiang

Jie Wang

Xiangying Deng

Abstract

Tumor immune escape is an important strategy of tumor survival. There are many mechanisms of tumor immune escape, including immunosuppression, which has become a research hotspot in recent years. The programmed death ligand-1/programmed death-1 (PD-L1/PD-1) signaling pathway is an important componen...

Subject

Tumor microenvironment

Immune system

PD-L1

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