Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses

Ovadia, Caroline; T. Seed, Paul; Sklavounos, Alexandros; Geenes, Victoria; Di Ilio, C.; Chambers, Jenny; Kohari, Katherine; Bacq, Yannick; Bozkurt, Nuray; Brun, R.; N. Bull, Laura; C. Estiú, Maria; Grymowicz, Monika; Günaydın, Berrin; M. Hague, William; Haslinger, Christian; Hu, Yayi; Kawakita, Tetsuya; Gül Kebapçılar, Ayşe; Kebapçılar, Levent; Kondrackienė, Jūratė; P. H. Koster, Maria; Kowalska-Kańka, Aneta; Kupčinskas, L.; H. Lee, Richard; Locatelli, Anna; I.R. Macı́as, Rocı́o; Marschall, Hanns–Ulrich; A. Oudijk, Martijn; Raz, Yael; Rimon, Eli; Shan, Dan; Shao, Yong; M. Tribe, Rachel; Trípodi, Valeria; Yayla Abide, Çiğdem; Yenidede, İlter; Thornton, Jim; C. Chappell, Lucy; Williamson, Catherine

doi:10.1016/s0140-6736(18)31877-4

Public

Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses

Published in The Lancet • Feb 14, 2019

Authors:

Caroline Ovadia

Paul T. Seed

Alexandros Sklavounos

Abstract

BACKGROUND: Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers is unclear. We aimed to quantify the adverse perinatal effects of intrahepatic cholestasis of pregnancy in women with increased ...

Subject

Medicine

Cholestasis of pregnancy

Bile acid

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