Predicting Alzheimer’s disease progression using multi-modal deep learning approach

Lee, Garam; Nho, Kwangsik; Kang, Byungkon; Sohn, Kyung-Ah; Kim, Dokyoon; Alzheimer’s Disease Neuroimaging Initiative, for; W. Weiner, Michael; Aisen, Paul; Petersen, Ronald; R. Jack, Clifford; J. Jagust, William; Q. Trojanowki, John; W. Toga, Arthur; Beckett, Laurel; C. Green, Robert; J. Saykin, Andrew; C. Morris, John; M. Shaw, Leslie; S. Khachaturian, Zaven; Sorensen, Greg; C. Carrillo, María; Kuller, Lew; Raichle, Marc; M. Paul, Steven; J. Davies, Peter; Fillit, Howard; Hefti, Franz; Holtzman, Davie; Mesulam, Marek-Marsel; Z. Potter, William; J. Snyder, Peter; Montine, Tom; G. Thomas, Ronald; Donohue, Michael; Walter, Sarah; Sather, Tamie; Jiminez, Gus; B. Balasubramanian, Archana; Mason, Jennifer; Sim, Iris; Harvey, Danielle; A. Bernstein, Matt; C. Fox, Nick; M. Thompson, Paul; Schuff, Norbert; DeCarli, Charles; Borowski, Bret; Gunter, Jeff; L. Senjem, Matthew; Vemuri, Prashanthi; Jones, David; Kantarci, Kejal; Ward, Chad; A. Koeppe, Robert; Foster, Norm; M. Reiman, Eric; Chen, Kewei; Mathis, Chet; Landau, Susan; J. Cairns, Nigel; Householder, Erin; Taylor‐Reinwald, Lisa; Lee, Virginia; Korecka, Magdalena; Figurski, Michal; Crawford, Karen; Neu, Scott; M. Foroud, Tatiana; Potkin, Steven; Shen, Li; Faber, Kelley; Kim, Sungeun; Tha, Lean; Frank, Richard; Hsiao, John; Kaye, Jeffrey; F. Quinn, Joseph; C. Silbert, Lisa; Lind, Betty; Carter, Raina; Dolen, Sara; M. Ances, Beau; Carroll, Maria; L. Creech, Mary; Franklin, Erin; A. Mintun, Mark; Schneider, Stacy; Oliver, Angela; S. Schneider, Lon; Pawluczyk, Sonia; Beccera, Mauricio; Teodoro, Liberty; M. Spann, Bryan; Brewer, James; Vanderswag, Helen; Fleisher, Adam; Marson, Daniel; Griffith, Randall; Clark, David; Geldmacher, David; Brockington, John; D. Roberson, Erik; Natelson Love, Marissa; L. Heidebrink, Judith; Lord, Joanne; S. Mason, Sara; S. Albers, Colleen; S. Knopman, David; Johnson, Kris; Grossman, Hillel; Mitsis, Effie; C. Shah, Raj; deToledo‐Morrell, Leyla; S. Doody, Rachelle; Villanueva‐Meyer, Javier; Chowdhury, Munir; Rountree, Susan; Dang, Mimi; Duara, Ranjan; Varón, Daniel; T. Greig, Maria; Roberts, Peggy; Stern, Yaakov; S. Honig, Lawrence; L. Bell, Karen; Albert, Marilyn; U. Onyike, Chiadi; D’Agostino, Daniel; Kielb, Stephanie; E. Galvin, James; Cerbone, Brittany; A. Michel, Christina; M. Pogorelec, Dana; Rusinek, Henry; J. de Leon, Mony; Glodzik, Lidia; De Santi, Susan; Womack, Kyle; Mathews, Dana; Quiceno, Mary; Murali Doraiswamy, P.; R. Petrella, Jeffrey; Borges‐Neto, Salvador; Z. Wong, Terence; Coleman, Edward; I. Levey, Allan; J. Lah, James; S. Cella, Janet; M. Burns, Jeffrey; H. Swerdlow, Russell; M. Brooks, William; E. Arnold, Steven; Karlawish, Jason; A. Wolk, David; Clark, Christopher; Apostolova, Liana; Tingus, Kathleen; Woo, Ellen; Silverman, Daniel; H. Lu, Po; Bartzokis, George; D. Smith, Charles; A. Jicha, Gregory; Hardy, Peter; Sinha, Partha; Oates, Elizabeth; Conrad, Gary; R. Graff‐Radford, Neill; Parfitt, Francine; Kendall, Tracy; Johnson, Heather; L. López, Oscar; Oakley, MaryAnn; M. Simpson, Donna; R. Farlow, Martin; Marie Hake, Ann; R. Matthews, Brandy; R. Brosch, Jared; Herring, Scott; Hunt, Cynthia; P. Porsteinsson, Anton; S. Goldstein, Bonnie; Martin, Kim; M. Makino, Kelly; Saleem Ismail, M.; Brand, Connie; A. Mulnard, Ruth; Thai, Gaby; Mc-Adams-Ortiz, Catherine; H. van Dyck, Christopher; E. Carson, Richard; G. MacAvoy, Martha; Varma, Pradeep; Chertkow, Howard; Bergman, Howard; Hosein, Chris; Black, Sandra; Stefanovic, Bojana; Caldwell, Curtis; Robin Hsiung, Ging‐Yuek; Feldman, Howard; Mudge, Benita; Assaly, Michele; Finger, Elizabeth; Pasternack, Stephen; Rachisky, Irina; Trost, Dick; Kertesz, Andrew; Bernick, Charles; Munic, Donna; Lipowski, Kristine; Weintraub, Masandra; Bonakdarpour, Borna; Kerwin, Diana; Wu, Chuang‐Kuo; Johnson, Nancy; Sadowsky, Carl; Villena, Teresa; Scott Turner, Raymond; Johnson, Kathleen; Reynolds, Brigid; A. Sperling, Reisa; A. Johnson, Keith; A. Marshall, Gad; A. Yesavage, Jerome; L. Taylor, Joy; Lane, Barton; Rosen, Allyson; Tinklenberg, Jared; N. Sabbagh, Marwan; M. Belden, Christine; A. Jacobson, Sandra; A. Sirrel, Sherye; W. Kowall, Neil; Killiany, Ronald; E. Budson, Andrew; Norbash, Alexander; Lynn Johnson, Patricia; O. Obisesan, Thomas; Wolday, Saba; Allard, Joanne; J. Lerner, Alan; Ogrocki, Paula; Tatsuoka, Curtis; Fatica, Parianne; Fletcher, Evan; Maillard, Pauline; Olichney, John; Carmichael, Owen; Kittur, Smita; Borrie, Michael; Lee, T.-Y.; Bartha, Robert; C. Johnson, Sterling; Asthana, Sanjay; M. Carlsson, Cynthia; Preda, Adrian; Nguyen, Dana; N. Tariot, Pierre; Burke, Anna; Trncic, Nadira; Fleisher, Adam; Reeder, Stephanie; Bates, Vernice; Capote, Horacio; Rainka, Michelle; W. Scharre, Douglas; Kataki, Maria; Adeli, Anahita; A. Zimmerman, Earl; Celmins, Dzintra; D. Brown, Alice; D. Pearlson, Godfrey; Blank, Karen; Anderson, Karen; A. Flashman, Laura; Seltzer, Marc; L. Hynes, Mary; B. Santulli, Robert; M. Sink, Kaycee; Gordineer, Leslie; D. Williamson, Jeff; Garg, Pradeep; Watkins, Franklin; R. Ott, Brian; Querfurth, Henry; Tremont, Geoffrey; Salloway, Stephen; Malloy, Paul; Correia, Stephen; J. Rosen, Howard; L. Miller, Bruce; C. Perry, David; Mintzer, Jacobo; Spicer, Kenneth; Bachman, David; Finger, Elizabeth; Pasternak, Stephen; Rachinsky, Irina; Rogers, John; Drost, Dick; Pomara, Nunzio; Hernando, Raymundo; Sarrael, Antero; K. Schultz, Susan; L. Boles Ponto, Laura; Shim, Hyungsub; Ekstam Smith, Karen; Relkin, Norman; Chaing, Gloria; Lin, Michael; Ravdin, Lisa; Smith, Amanda; Ashok Raj, Balebail; Fargher, Kristin

doi:10.1038/s41598-018-37769-z

Public

Predicting Alzheimer’s disease progression using multi-modal deep learning approach

Published in Scientific Reports • Feb 13, 2019

Authors:

Garam Lee

Kwangsik Nho

Byungkon Kang

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative condition marked by a decline in cognitive functions with no validated disease modifying treatment. It is critical for timely treatment to detect AD in its earlier stage before clinical manifestation. Mild cognitive impairment (MCI) is an i...

Subject

Alzheimer's Disease Neuroimaging Initiative

Neuroimaging

Cognition

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!