Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade.

F, Zhou; B, Feng; H, Yu; D, Wang; T, Wang; Y, Ma; S, Wang; Y, Li

doi:10.1002/adma.201805888

Public

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade.

Shared by NobleBlocks on Feb 14, 2019 • 12:00 AM UTC

Authors:

Zhou F

Feng B

Yu H

Abstract

Chemoimmunotherapy is reported to activate a robust T cell antitumor immune response by triggering immunogenic cell death (ICD), which has initiated a number of clinical trials. However, current chemoimmunotherapy is restricted to a small fraction of patients due to low drug delivery efficacy and im...

Subject

Cancer Immunotherapy

Tumor Microenvironment

Immunogenic Cell Death

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