Alterations in Gut Glutamate Metabolism Associated with Changes in Gut Microbiota Composition in Children with Autism Spectrum Disorder

Wang, Mingbang; Wan, Jing; Rong, Han; He, Fusheng; Wang, Hui; Zhou, Jiaxiu; Cai, C; Wang, Yan; Xu, Ruihuan; Yin, Zhaoqing; Zhou, Wenhao

doi:10.1128/msystems.00321-18

Public

Alterations in Gut Glutamate Metabolism Associated with Changes in Gut Microbiota Composition in Children with Autism Spectrum Disorder

Published in mSystems • Jan 28, 2019

Authors:

Mingbang Wang

Jing Wan

Han Rong

Abstract

Multiple lines of evidence suggest that the gut microbiota may play an important role in the pathogenesis of ASD, but the specific mechanism is still unclear. Through a comprehensive gut metagenomic and metabolome study of children with ASD, alterations in gut metabolite composition were found in ch...

Subject

Gut flora

Gut–brain axis

Metagenomics

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