Panton–Valentine leucocidin is the key determinant of Staphylococcus aureus pyomyositis in a bacterial GWAS

C Young, Bernadette; G Earle, Sarah; Soeng, Sona; Sar, Poda; Kumar, Varun; Hor, Songly; Sar, Vuthy; Bousfield, Rachel; D Sanderson, Nicholas; Barker, Leanne; Stoesser, Nicole; RW Emary, Katherine; M Parry, Christopher; K Nickerson, Emma; Turner, Paul; Bowden, Rory; W Crook, Derrick; H Wyllie, David; PJ Day, Nicholas; J Wilson, Daniel; E Moore, Catrin

doi:10.7554/elife.42486

Public

Panton–Valentine leucocidin is the key determinant of Staphylococcus aureus pyomyositis in a bacterial GWAS

Shared by NobleBlocks on Feb 22, 2019 • 12:00 AM UTC

Authors:

Bernadette C Young

Sarah G Earle

Sona Soeng

Abstract

Pyomyositis is a severe bacterial infection of skeletal muscle, commonly affecting children in tropical regions, predominantly caused by Staphylococcus aureus. To understand the contribution of bacterial genomic factors to pyomyositis, we conducted a genome-wide association study of S. aureus cultur...

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