The MLL recombinome of acute leukemias in 2017

Meyer, Claus; Burmeister, Thomas; Gröger, Daniela; Tsaur, Grigory; Г. Фечина, Л.; Renneville, Aline; Sutton, Rosemary; C. Venn, Nicola; Emerenciano, Mariana; S. Pombo‐de‐Oliveira, Maria; Barbieri Blunck, Caroline; A. Lopes, Bruno; Zuna, Jan; Trka, Jan; Ballerini, Paola; Lapillonne, Hélène; De Braekeleer, Marc; Cazzaniga, Giovanni; Corral Abascal, L; H. J. van der Velden, Vincent; Delabesse, Éric; S Park, T; Hwan Oh, Seung; Luiza Macedo Silva, Maria; Lund-Aho, T; Juvonen, Vesa; S. Moore, Andrew; Heidenreich, Olaf; Vormoor, Josef; Zerkalenkova, Elena; Olshanskaya, Yulia; Bueno, Clara; Menéndez, Pablo; Teigler‐Schlegel, Andrea; zur Stadt, Udo; Lentes, Jana; Göhring, Gudrun; Kustanovich, Anatoly; Aleinikova, Olga; W. Schäfer, Beat; Kubetzko, Susanne; O Madsen, H; Gruhn, Bernd; Duarte, Ximo; Gameiro, Paula; Lippert, Éric; Bidet, Audrey; M Cayuela, J; Clappier, Emmanuelle; N. Alonso, Cristina; Michel Zwaan, C.; M. van den Heuvel‐Eibrink, Marry; Izraeli, Shai; Trakhtenbrot, L.; A. Archer, Paul; Hancock, Jerry; Möricke, Anja; Alten, Julia; Schrappe, Martin; Stanulla, Martin; Strehl, Sabine; Attarbaschi, Andishe; Dworzak, Michael; A. Haas, Oskar; Panzer-Grümayer, R; Sędek, Łukasz; Szczepański, Tomasz; Caye, Aurélie; Suarez, Lydia; Cavé, Hélène; Marschalek, Rolf

doi:10.1038/leu.2017.213

Public

The MLL recombinome of acute leukemias in 2017

Published in Leukemia • Jul 13, 2017

Authors:

Claus Meyer

Thomas Burmeister

Daniela Gröger

Abstract

Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant, pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained from 2345 acute leukemia patients. Genomic breakpoints within the MLL gene and the involved translocation partner genes (TPGs) we...

Subject

Breakpoint

Chromosomal translocation

Biology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!