EMT is associated with an epigenetic signature of ECM remodeling genes

Peixoto, Paul; Etcheverry, Amandine; Aubry, Marc; Missey, Anaïs; Lachat, Camille; Perrard, Jérôme; Hendrick, Elodie; Delage-Mourroux, Régis; Mosser, Jean; Borg, Christophe; Feugeas, Jean‐Paul; Herfs, Michaël; Boyer‐Guittaut, Michaël; Hervouet, Éric

doi:10.1038/s41419-019-1397-4

Public

EMT is associated with an epigenetic signature of ECM remodeling genes

Published in Cell Death and Disease • Feb 27, 2019

Authors:

Paul Peixoto

Amandine Etcheverry

Marc Aubry

Abstract

Type III epithelial-mesenchymal transition (EMT) has been previously associated with increased cell migration, invasion, metastasis, and therefore cancer aggressiveness. This reversible process is associated with an important gene expression reprogramming mainly due to epigenetic plasticity. Neverth...

Subject

Epigenetics

Gene

Gene signature

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