Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

B. Postuma, Ronald; Iranzo, Álex; Hu, Michele; Högl, Birgit; F. Boeve, Bradley; Manni, Raffaele; H. Oertel, Wolfgang; Arnulf, Isabelle; Ferini‐Strambi, Luigi; Puligheddu, Monica; Antelmi, Elena; Cochen De Cock, Valérie; Arnaldi, Dario; Mollenhauer, Brit; Videnović, Aleksandar; Šonka, Karel; Jung, Ki‐Young; Kunz, Dieter; Dauvilliers, Yves; Provini, Federica; J.G. Lewis, Simon; Bušková, Jitka; Pavlova, Milena; Heidbreder, Anna; Montplaisir, Jacques; Santamaría, Joan; R. Barber, Thomas; Stefani, Ambra; K. St. Louis, Erik; Terzaghi, Michele; Janzen, Annette; Leu-Semenescu, Smandra; Plazzi, Giuseppe; Nobili, Flavio; Sixel-Doering, F.; Dušek, Petr; Bes, Frédérik; Cortelli, Pietro; A. Ehgoetz Martens, Kaylena; Gagnon, Jean‐François; Gaig, Carles; Zucconi, Marco; Trenkwalder, Claudia; Gan‐Or, Ziv; Lo, Christine; Rolinski, Michal; Mahlknecht, Philipp; Holzknecht, Evi; R Boeve, Angel; Teigen, Luke; Toscano, Gianpaolo; Mayer, Geert; Morbelli, Silvia; Dawson, Benjamin; Pelletier, Amélie

doi:10.1093/brain/awz030

Public

Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

Published in Brain • Jan 26, 2019

Authors:

Ronald B. Postuma

Álex Iranzo

Michele Hu

Abstract

Idiopathic REM sleep behaviour disorder (iRBD) is a powerful early sign of Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. This provides an unprecedented opportunity to directly observe prodromal neurodegenerative states, and potentially intervene with neuroprotective th...

Subject

Parkinsonism

Dementia

REM sleep behavior disorder

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