Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication

Loh, Chin-Yap; Arya, Aditya; Fadhil Naema, Ahmed; Fen Wong, Won; Sethi, Gautam; Yeng Looi, Chung

doi:10.3389/fonc.2019.00048

Public

Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication

Published in Frontiers in Oncology • Feb 21, 2019

Authors:

Chin-Yap Loh

Aditya Arya

Ahmed Fadhil Naema

Abstract

Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream with Janus kinases (JAK) family protein and capable of integrating inputs from different signaling pathways. Each family member plays unique functions in signal transduction and crucial in mediating cellular respon...

Subject

STAT5

STAT3

STAT protein

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