Transplantation of bone marrow mesenchymal stromal cells attenuates liver fibrosis in mice by regulating macrophage subtypes

Luo, Xiaoyu; Meng, Xiangjun; Cao, Dachun; Wang, Wei; Zhou, Kun; Li, Lei; Guo, Mei; Wang, Ping

doi:10.1186/s13287-018-1122-8

Public

Transplantation of bone marrow mesenchymal stromal cells attenuates liver fibrosis in mice by regulating macrophage subtypes

Published in Stem Cell Research & Therapy • Jan 11, 2019

Authors:

Xiaoyu Luo

Xiangjun Meng

Dachun Cao

Abstract

BACKGROUND: Liver fibrosis is a key phase that will progress to further injuries such as liver cirrhosis or carcinoma. This study aimed to investigate whether transplantation of bone marrow mesenchymal stromal cells (BM-MSCs) can attenuate liver fibrosis in mice and the underlying mechanisms based o...

Subject

Mesenchymal stem cell

Stromal cell

Bone marrow

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!