Measuring particle size distribution of nanoparticle enabled medicinal products, the joint view of EUNCL and NCI-NCL. A step by step approach combining orthogonal measurements with increasing complexity

Caputo, Fanny; D. Clogston, Jeffrey; Calzolai, Luigi; Rösslein, Matthias; Prina‐Mello, Adriele

doi:10.1016/j.jconrel.2019.02.030

Public

Measuring particle size distribution of nanoparticle enabled medicinal products, the joint view of EUNCL and NCI-NCL. A step by step approach combining orthogonal measurements with increasing complexity

Published in Journal of Controlled Release • Feb 21, 2019

Authors:

Fanny Caputo

Jeffrey D. Clogston

Luigi Calzolai

Abstract

The particle size distribution (PSD) and the stability of nanoparticles enabled medicinal products (NEP) in complex biological environments are key attributes to assess their quality, safety and efficacy. Despite its low resolution, dynamic light scattering (DLS) is the most common sizing technique ...

Subject

Sizing

Nanoparticle tracking analysis

Computer science

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