The relation between PI3K/AKT signalling pathway and cancer

Noorolyai, Saeed; Shajari, Neda; Baghbani, Elham; Sadreddini, Sanam; Baradaran, Behzad

doi:10.1016/j.gene.2019.02.076

Public

The relation between PI3K/AKT signalling pathway and cancer

Published in Gene • Mar 5, 2019

Authors:

Saeed Noorolyai

Neda Shajari

Elham Baghbani

Abstract

Phosphatidylinositol 3-kinases (PI3Ks) are crucial coordinators of intracellular signalling in response to the extracellular stimulators. Hyperactivation of PI3K signalling cascades is one among the most ordinary events in human cancers. Focusing on the PI3K pathway remains both a chance and a chall...

Subject

PI3K/AKT/mTOR pathway

PTEN

Biology

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