Evaluation of Miracle Mouthwash plus Hydrocortisone Versus Prednisolone Mouth Rinses as Prophylaxis for Everolimus-Associated Stomatitis: A Randomized Phase II Study

Jones, Vicky; McIntyre, Kristi; Paul, Devchand; Wilks, Sharon; M. Ondreyco, Sharon; Sedlacek, Scot; Melnyk, Anton; P. Oommen, Sanjay; Wang, Yunfei; Peck, Susan; O’Shaughnessy, Joyce

doi:10.1634/theoncologist.2018-0340

Public

Evaluation of Miracle Mouthwash plus Hydrocortisone Versus Prednisolone Mouth Rinses as Prophylaxis for Everolimus-Associated Stomatitis: A Randomized Phase II Study

Published in The Oncologist • Mar 4, 2019

Authors:

Vicky Jones

Kristi McIntyre

Devchand Paul

Abstract

BACKGROUND: Mammalian target of rapamycin (mTOR) inhibitor-associated stomatitis (mIAS) is a frequent adverse event (AE) associated with mTOR inhibitor therapy and can impact treatment adherence. The objectives are to evaluate two steroid-based mouthrinses for preventing/ameliorating mIAS in patient...

Subject

Mouth rinse

Randomized controlled trial

Medicine

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