Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective

Damoiseaux, Jan; Eduardo Coelho Andrade, Luís; Gabriel Carballo, Orlando; Conrad, Karsten; Luiz Carvalho Francescantônio, Paulo; J. Fritzler, Marvin; García‐De La Torre, Ignacio; Herold, Manfred; Klotz, Werner; de Melo Cruvinel, Wilson; Mimori, Tsuneyo; Alberto von Mühlen, Carlos; Satoh, Minoru; K. L. Chan, Edward

doi:10.1136/annrheumdis-2018-214436

Public

Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective

Published in Annals of the Rheumatic Diseases • Mar 12, 2019

Authors:

Jan Damoiseaux

Luís Eduardo Coelho Andrade

Orlando Gabriel Carballo

Abstract

The indirect immunofluorescence assay (IIFA) on HEp-2 cells is widely used for detection of antinuclear antibodies (ANA). The dichotomous outcome, negative or positive, is integrated in diagnostic and classification criteria for several systemic autoimmune diseases. However, the HEp-2 IIFA test has ...

Subject

Medicine

Anti-nuclear antibody

Context (archaeology)

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