Mutations in <i>NLRP2</i> and <i>NLRP5</i> cause female infertility characterised by early embryonic arrest

Mu, Jian; Wang, Wenjing; Chen, Biaobang; Wu, Ling; Li, Bin; Mao, Xiaoyan; Zhang, Zhihua; Fu, Jing; Kuang, Yanping; Sun, Xiaoxi; Li, Qiaoli; Li, Jin; He, Lin; Sang, Qing; Wang, Lei

doi:10.1136/jmedgenet-2018-105936

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Mutations in NLRP2 and NLRP5 cause female infertility characterised by early embryonic arrest

Published in Journal of Medical Genetics • Mar 15, 2019

Authors:

Jian Mu

Wenjing Wang

Biaobang Chen

Abstract

BACKGROUND: Successful human reproduction requires normal spermatogenesis, oogenesis, fertilisation and early embryonic development, and abnormalities in any of these processes will result in infertility. Early embryonic arrest is commonly observed in infertile patients with recurrent failure of ass...

Subject

Biology

Embryonic stem cell

Sanger sequencing

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